33^rd European Diabetes Congress

Pituitary and Adrenal disorders

The pituitary is a tiny secreter (about the scale of a excretory organ bean) situated at the bottom of the brain, simply below the optic (eye) nerve in a very bony space called the sella turcica. It is created of the anterior (adenohypophysis) and posterior (neurohypophysis) endocrine. It is usually referred to as the “master gland” as a result of it produces variety of endocrines that regulate different hormone glands within the body.

Cushing's disease is a rare condition caused by associate degree overrun of the adrenal internal secretion Cortef. The most common form of Cushing's disease is due to an excess secretion of the pituitary hormone, ACTH (adrenocorticotropic hormone), which circulates in the blood and stimulates the adrenal gland.

The adrenal glands are located just above the kidneys and produce three major hormones, two of which originate in the outer adrenal cortex (cortisol and aldosterone) and the other from the inner adrenal medulla (epinephrine):

Cortisol, an important hormone for the regulation of glucose and protein metabolism, as well as blood pressure and the immune system.

Aldosterone, a hormone involved in blood pressure, sodium and potassium balance.

Epinephrine (adrenalin), a major hormone of the sympathetic nervous system and the “fight-or-flight” response.

Adrenal insufficiency involves reduced hormone secretion from the adrenal gland, resulting in a deficiency of all adrenal hormones, including cortisol and aldosterone