33^rd European Diabetes Congress

Genetics and Gene Regulation

Diabetes constitutes a major public health problem. Although substantial progress has been made in defining the genetics of metabolic syndrome risk for specific subtypes of diabetes the majority of genetic risk of diabetes remain unresolved. This review focuses on the current knowledge of the genetic basis of diabetes and its complications, specifically diabetic nephropathy (DN), recent advances in genetics of diabetes, diabetes in ethnic groups, genetic lifestyle interactions and understanding the genetics of Diabetes. Ultimately, identification of genes that contribute to risk of diabetes and its complications will allow identification of patients who have diabetes and are at risk and targeted treatment/interventional strategies.