21^st Asia Pacific Diabetes Conference

Therapeutic Advances In Endocrinology And Metabolism

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Weight control, diet and exercise play a critical role in controlling diabetes.

Other options are:

• Insulin injections: Using a very thin needle, the patient injects insulin through the arm, leg or stomach wall every day.
• Oral drugs: Specific drugs can often lower blood sugar levels in people with type 2 diabetes by prompting the pancreas to release insulin and increasing its ability to work. Other types of oral drugs do not affect the release of insulin but increase the body's response to its own insulin.

Without treatment diabetes insipidus can cause permanent kidney damage.

Treatment usually consists of hormone replacement and treatment of any underlying cause (such as surgical removal of a pituitary tumor) that can be addressed.

Non-hormone drugs may also be helpful, including:

• Diuretics
• ADH-releasing drugs such as chlorpropamide, carbamazepine and clofibrate. These can reduce or eliminate the need for hormone replacement in some people who have a partial lack of vasopressin. These drugs are not effective, however, if a person has nephrogenic diabetes insipidus.
• Prostglandin inhibitors

Reducing the amount of salt consumed in the diet may also help.