Treatment and Diagnosis of Endocrine Diseases

The mental and neurological deviations in cretinism are the direct result of thyroxine deficiency and not due to an associated congenital defect. In the treatment of thyrotoxicosis in childhood, preference is given to the use of anti-thyroid drugs rather than to surgery. Generous reference is made to papers by British authors (both in this section and throughout the book), but there is no mention of the observation of P. R. Evans (Pediatrics, 1952, 41, 706) on the vertebral changes in hypothyroidism. Pediatricians will turn eagerly to the account of adrenocortical hyperplasia, for most of the dramatic advances in this field have been the work of the author and his associates. In the maintenance treatment of congenital virilism he recommends 25-75 mg. of intramuscular cortisone every third day and two to five DCA pellets of 125 mg. each by implant in the salt-losing type with the addition of 2 to 3 g. of sodium chloride daily. The need to watch height increments in these children as well as 17-ketosteroid output is emphasized.

  • Primary hyperparathyroidism
  • Secondary hyperparathyroidism
  • Hypoparathyroidism
  • Pseudohypoparathyroidism

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