Endocrine complications

Endocrine disorders  are often quite complex, involving a mixed picture of hyposecretion and hypersecretion because of the feedback mechanisms involved in the endocrine system. For example, most forms of hyperthyroidism are associated with an excess of thyroid hormone and a low level of thyroid stimulating hormone. Patients with multi-transfused thalassemia major may develop severe endocrine complications due to iron overload. The anterior pituitary is particularly sensitive to iron overload which disrupts hormonal secretion resulting in hypogonadism, short stature , acquired hypothyroidism and hypoparathyroidism. Glucose intolerance and diabetes mellitus are also common in thalassaemic patients. Delayed or absent puberty and hypogonadism may result in fertility problems which affect enormously the life of thalassemics. Glucose intolerance in adolescence and diabetes mellitus later in life are also frequent complications mainly due to iron overload, chronic liver disease and genetic predisposition. Primary hypothyroidism and hypoparathyroidsm usually appear in the second decade of life; are related to iron overload and may be reversible at an early stage by intensive chelation. Osteopenia and osteoporosis due to a complicated pathogenesis represent prominent causes of morbidity in young adults of both genders with thalassaemia. Early recognition and prevention of the endocrine complications, by early and regular chelation therapy, is mandatory for the improvement of the quality of life and psychological outcome of these patients.

  • Growth retardation
  • Delayed Puberty and Hypogonadism
  • Fertility Disorders (Amenorrhea & Polycystic ovary syndrome)
  • Hysterosalpingography
  • Impaired carbohydrate metabolism
  • Chelation Toxicity
  • Lupus Erythematosus and Sjogren Syndrome
  • Anorexia nervosa (AN)

Related Conference of Endocrine complications

September 20-21, 2017

International Conference on Diabetes and Diabetic Nursing Care

Charlotte, North Carolina, USA
October 30- November 1, 2017

9th Annual Congress on Endocrine Disorders and Therapies


(10 Plenary Forums - 1 Event)
Chicago, Illinois, USA
December 04-05, 2017

25th Global Diabetes Summit and Medicare Expo

Dubai, UAE
October 30-November 01, 2017

10th International Conference on Endocrinology

Chicago, Illinois, USA
February 12-13,2018

7th European Diabetes and Endocrinology Congress

Munich, Germany
March 8-9, 2018

17th Global Diabetes Conference & Nursing Care

Paris, France
March 19-20, 2018

11th Diabetologists Conference

New York, USA
June 11-12, 2018

27th European Diabetes Congress

Rome, Italy
June 18-19, 2018

3rd International Conference on Metabolic Syndrome

Dublin, Ireland
July 9-10, 2018 Sydney, Australia

20th Asia Pacific Diabetes Conference

Endocrine complications Conference Speakers

Recommended Sessions

Related Journals

Are you interested in